CADD-04. NANOPARTICLE DELIVERY OF miRNAs TO INHIBIT GBM STEM CELLS
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چکیده
منابع مشابه
Gene Delivery to Mesenchymal Stem Cells
There is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. These studies encompass different applications from targeted homing of Mesenchymal Stromal (stem) Cells (MSC), to arming them with different cytokines. Resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...
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Introduction: IIron oxide nanoparticles (IO NP) have an increasing number of biomedical applications. To date, the potential cytotoxicity of these particles remains an issue of debate. Little is known about the cellular interaction or toxic effects of IO NP on differentiation of stem cells. The aim of the present study was to investigate the possible toxic role of different doses of IO NP in di...
متن کاملgene delivery to mesenchymal stem cells
there is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. these studies encompass different applications from targeted homing of mesenchymal stromal (stem) cells (msc), to arming them with different cytokines. resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...
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We created a 3D cell co-culture model by combining nanoengineered mesenchymal stem cells (MSCs) with the metastatic breast cancer cell line MDA-MD-231 and primary breast cancer cell line MCF7 to explore the transfer of quantum dots (QDs) to cancer cells. First, the optimal conditions for high-content QD loading in MSCs were established. Then, QD uptake in breast cancer cells was assessed after ...
متن کاملAuthor ' s response to reviews Title : miR - 124 a and miR - 137 inhibit proliferation of GBM cells and induce differentiation of tumor stem cells
Joachim Silber ([email protected]) Daniel A Lim ([email protected]) Claudia Petritsch ([email protected]) Anders I Persson ([email protected]) Alika K Maunakea ([email protected]) Mamie Yu ([email protected]) Scott R Vandenberg ([email protected]) David G Ginzinger ([email protected]) C David James ([email protected]) Joseph F Costello (Joseph.Costello@uc...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2018
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/noy148.1153